FFV51 possesses antioxidant properties and androgenic activities that influence reproductive factors and hormones. Antioxidants serve as the first line of defense against free radicals produced by oxidative stress (OS). They remove reactive oxygen species (ROS), enhance endometrial receptivity, and improve fertility.
Male infertility is often associated with increased oxidative stress and low glutathione (GSH) levels. Elevated GSH levels may improve sperm quality and enhance fertility, making it an essential nutrient for male reproductive health. Female infertility refers to difficulties in conceiving in women. It can be primary, in women who have never conceived, or secondary, in women who have previously conceived. The most common causes of female infertility include ovulation problems, damage to the fallopian tubes or uterus, and cervical issues. Age is also a contributing factor, as fertility naturally declines as a woman gets older.
FFV51 can be highly effective in re-balancing hormones, as well as improving the overall health of partners—both of which are crucial for successful conception. The present review aims to compile available information on various natural exogenous factors that demonstrate potential beneficial activity in the male reproductive system.
The studies presented here highlight the potential of FFV51 as a protective agent and a novel supplementary therapy for the recovery of impaired spermatogenesis and male infertility. Similarly, FFV51 may support the recovery of impaired ovogenesis and female infertility.